diff --git a/changelog.d/16114.feature b/changelog.d/16114.feature
new file mode 100644
index 0000000000..e937a3b029
--- /dev/null
+++ b/changelog.d/16114.feature
@@ -0,0 +1 @@
+Add an `admins` query parameter to the [List Accounts](https://matrix-org.github.io/synapse/v1.91/admin_api/user_admin_api.html#list-accounts) [admin API](https://matrix-org.github.io/synapse/v1.91/usage/administration/admin_api/index.html), to include only admins or to exclude admins in user queries.
\ No newline at end of file
diff --git a/docs/admin_api/user_admin_api.md b/docs/admin_api/user_admin_api.md
index c269ce6af0..99abfea3a0 100644
--- a/docs/admin_api/user_admin_api.md
+++ b/docs/admin_api/user_admin_api.md
@@ -219,6 +219,8 @@ The following parameters should be set in the URL:
   **or** displaynames that contain this value.
 - `guests` - string representing a bool - Is optional and if `false` will **exclude** guest users.
   Defaults to `true` to include guest users.
+- `admins` - Optional flag to filter admins. If `true`, only admins are queried. If `false`, admins are excluded from 
+  the query. When the flag is absent (the default), **both** admins and non-admins are included in the search results.
 - `deactivated` - string representing a bool - Is optional and if `true` will **include** deactivated users.
   Defaults to `false` to exclude deactivated users.
 - `limit` - string representing a positive integer - Is optional but is used for pagination,
diff --git a/synapse/rest/admin/users.py b/synapse/rest/admin/users.py
index 04d9ef25b7..240e6254b0 100644
--- a/synapse/rest/admin/users.py
+++ b/synapse/rest/admin/users.py
@@ -109,6 +109,8 @@ class UsersRestServletV2(RestServlet):
             )
         deactivated = parse_boolean(request, "deactivated", default=False)
 
+        admins = parse_boolean(request, "admins")
+
         # If support for MSC3866 is not enabled, apply no filtering based on the
         # `approved` column.
         if self._msc3866_enabled:
@@ -146,6 +148,7 @@ class UsersRestServletV2(RestServlet):
             name,
             guests,
             deactivated,
+            admins,
             order_by,
             direction,
             approved,
diff --git a/synapse/storage/databases/main/__init__.py b/synapse/storage/databases/main/__init__.py
index be67d1ff22..e17f25e87a 100644
--- a/synapse/storage/databases/main/__init__.py
+++ b/synapse/storage/databases/main/__init__.py
@@ -168,6 +168,7 @@ class DataStore(
         name: Optional[str] = None,
         guests: bool = True,
         deactivated: bool = False,
+        admins: Optional[bool] = None,
         order_by: str = UserSortOrder.NAME.value,
         direction: Direction = Direction.FORWARDS,
         approved: bool = True,
@@ -184,6 +185,9 @@ class DataStore(
             name: search for local part of user_id or display name
             guests: whether to in include guest users
             deactivated: whether to include deactivated users
+            admins: Optional flag to filter admins. If true, only admins are queried.
+                    if false, admins are excluded from the query. When it is
+                    none (the default), both admins and none-admins are queried.
             order_by: the sort order of the returned list
             direction: sort ascending or descending
             approved: whether to include approved users
@@ -220,6 +224,12 @@ class DataStore(
             if not deactivated:
                 filters.append("deactivated = 0")
 
+            if admins is not None:
+                if admins:
+                    filters.append("admin = 1")
+                else:
+                    filters.append("admin = 0")
+
             if not approved:
                 # We ignore NULL values for the approved flag because these should only
                 # be already existing users that we consider as already approved.
diff --git a/tests/rest/admin/test_user.py b/tests/rest/admin/test_user.py
index 41a959b4d6..feb81844ae 100644
--- a/tests/rest/admin/test_user.py
+++ b/tests/rest/admin/test_user.py
@@ -879,6 +879,44 @@ class UsersListTestCase(unittest.HomeserverTestCase):
         self._order_test([self.admin_user, user1, user2], "creation_ts", "f")
         self._order_test([user2, user1, self.admin_user], "creation_ts", "b")
 
+    def test_filter_admins(self) -> None:
+        """
+        Tests whether the various values of the query parameter `admins` lead to the
+        expected result set.
+        """
+
+        # Register an additional non admin user
+        self.register_user("user", "pass", admin=False)
+
+        # Query all users
+        channel = self.make_request(
+            "GET",
+            f"{self.url}",
+            access_token=self.admin_user_tok,
+        )
+        self.assertEqual(200, channel.code, channel.result)
+        self.assertEqual(2, channel.json_body["total"])
+
+        # Query only admin users
+        channel = self.make_request(
+            "GET",
+            f"{self.url}?admins=true",
+            access_token=self.admin_user_tok,
+        )
+        self.assertEqual(200, channel.code, channel.result)
+        self.assertEqual(1, channel.json_body["total"])
+        self.assertEqual(1, channel.json_body["users"][0]["admin"])
+
+        # Query only non admin users
+        channel = self.make_request(
+            "GET",
+            f"{self.url}?admins=false",
+            access_token=self.admin_user_tok,
+        )
+        self.assertEqual(200, channel.code, channel.result)
+        self.assertEqual(1, channel.json_body["total"])
+        self.assertFalse(channel.json_body["users"][0]["admin"])
+
     @override_config(
         {
             "experimental_features": {